BDBM60844 US9174940, 4

SMILES: CC(=O)N1c2ccc(NC(=O)c3ccccn3)cc2C(C)(CC1(C)C)c1ccccc1

InChI Key: InChIKey=YDZOMCRPHBKBDJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 60844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid-stimulating hormone receptor (TSH) (Homo sapiens (Human))	BDBM60844 (US9174940, 4) Show SMILES CC(=O)N1c2ccc(NC(=O)c3ccccn3)cc2C(C)(CC1(C)C)c1ccccc1 Show InChI InChI=1S/C26H27N3O2/c1-18(30)29-23-14-13-20(28-24(31)22-12-8-9-15-27-22)16-21(23)26(4,17-25(29,2)3)19-10-6-5-7-11-19/h5-16H,17H2,1-4H3,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme B.V. US Patent					Assay Description Antagonist activity of three test compounds against human TSI at the human TSH receptor was tested in Chinese Hamster Ovary (CHO) cells (cultured 16 ...				US Patent US9174940 (2015) BindingDB Entry DOI: 10.7270/Q2F18XJC
					More data for this Ligand-Target Pair