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SMILES: CN1CCN(C1=O)c1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608852 (US11702409, Example 13a | US11702409, Example 13b) Show SMILES CN1CCN(C1=O)c1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(9.19,-2.83,;7.78,-3.45,;7.46,-4.96,;5.93,-5.12,;5.3,-3.71,;6.45,-2.68,;6.05,-1.2,;3.84,-3.24,;3.52,-1.73,;2.05,-1.26,;.91,-2.29,;1.23,-3.79,;2.69,-4.27,;-.56,-1.81,;-1.03,-.35,;-2.57,-.35,;-3.34,.99,;-4.83,1.39,;-4.43,2.87,;-2.94,2.48,;-5.92,3.27,;-5.52,4.76,;-4.03,4.36,;-6.61,5.85,;-6.21,7.34,;-8.1,5.45,;-9.19,6.54,;-3.05,-1.81,;-4.51,-2.29,;-1.8,-2.72,;-1.8,-4.26,;-3.14,-5.03,;-4.47,-4.26,;-3.14,-6.57,;-4.47,-7.34,;-1.8,-7.34,;-.47,-6.57,;1,-7.04,;1.9,-5.8,;1,-4.55,;-.47,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608852 (US11702409, Example 13a | US11702409, Example 13b) Show SMILES CN1CCN(C1=O)c1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(9.19,-2.83,;7.78,-3.45,;7.46,-4.96,;5.93,-5.12,;5.3,-3.71,;6.45,-2.68,;6.05,-1.2,;3.84,-3.24,;3.52,-1.73,;2.05,-1.26,;.91,-2.29,;1.23,-3.79,;2.69,-4.27,;-.56,-1.81,;-1.03,-.35,;-2.57,-.35,;-3.34,.99,;-4.83,1.39,;-4.43,2.87,;-2.94,2.48,;-5.92,3.27,;-5.52,4.76,;-4.03,4.36,;-6.61,5.85,;-6.21,7.34,;-8.1,5.45,;-9.19,6.54,;-3.05,-1.81,;-4.51,-2.29,;-1.8,-2.72,;-1.8,-4.26,;-3.14,-5.03,;-4.47,-4.26,;-3.14,-6.57,;-4.47,-7.34,;-1.8,-7.34,;-.47,-6.57,;1,-7.04,;1.9,-5.8,;1,-4.55,;-.47,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair