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SMILES: CN(C)CCn1cc2cc(ccc2n1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608859 (US11702409, Example 16a | US11702409, Example 16b) Show SMILES CN(C)CCn1cc2cc(ccc2n1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(5.96,.58,;7.44,.98,;7.84,2.47,;8.53,-.11,;8.13,-1.59,;6.65,-1.99,;5.5,-.96,;4.17,-1.73,;2.7,-1.26,;1.56,-2.29,;1.88,-3.79,;3.35,-4.27,;4.49,-3.24,;6.02,-3.4,;.1,-1.81,;-.38,-.35,;-1.92,-.35,;-2.69,.99,;-4.18,1.39,;-3.78,2.87,;-2.29,2.48,;-5.27,3.27,;-4.87,4.76,;-3.38,4.36,;-5.96,5.85,;-5.56,7.34,;-7.44,5.45,;-8.53,6.54,;-2.4,-1.81,;-3.86,-2.29,;-1.15,-2.72,;-1.15,-4.26,;-2.48,-5.03,;-3.82,-4.26,;-2.48,-6.57,;-3.82,-7.34,;-1.15,-7.34,;.18,-6.57,;1.65,-7.04,;2.55,-5.8,;1.65,-4.55,;.18,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608859 (US11702409, Example 16a | US11702409, Example 16b) Show SMILES CN(C)CCn1cc2cc(ccc2n1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(5.96,.58,;7.44,.98,;7.84,2.47,;8.53,-.11,;8.13,-1.59,;6.65,-1.99,;5.5,-.96,;4.17,-1.73,;2.7,-1.26,;1.56,-2.29,;1.88,-3.79,;3.35,-4.27,;4.49,-3.24,;6.02,-3.4,;.1,-1.81,;-.38,-.35,;-1.92,-.35,;-2.69,.99,;-4.18,1.39,;-3.78,2.87,;-2.29,2.48,;-5.27,3.27,;-4.87,4.76,;-3.38,4.36,;-5.96,5.85,;-5.56,7.34,;-7.44,5.45,;-8.53,6.54,;-2.4,-1.81,;-3.86,-2.29,;-1.15,-2.72,;-1.15,-4.26,;-2.48,-5.03,;-3.82,-4.26,;-2.48,-6.57,;-3.82,-7.34,;-1.15,-7.34,;.18,-6.57,;1.65,-7.04,;2.55,-5.8,;1.65,-4.55,;.18,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair