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SMILES: Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1cnc(N)c(F)c1)-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608870 (US11702409, Example 20a | US11702409, Example 20b) Show SMILES Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1cnc(N)c(F)c1)-c1c(Cl)c(C)cc2[nH]ncc12 |(-3.12,-2.83,;-1.65,-2.36,;-.41,-3.26,;.84,-2.36,;.36,-.89,;-1.18,-.89,;-1.95,.44,;-3.43,.84,;-3.03,2.33,;-1.55,1.93,;-4.52,2.73,;-4.12,4.22,;-2.64,3.82,;-5.21,5.3,;-6.7,4.91,;-4.81,6.79,;-5.9,7.88,;2.31,-2.83,;3.45,-1.8,;4.91,-2.28,;5.23,-3.78,;6.7,-4.26,;4.09,-4.81,;4.41,-6.32,;2.63,-4.34,;-.41,-4.8,;-1.74,-5.57,;-3.07,-4.8,;-1.74,-7.11,;-3.07,-7.88,;-.41,-7.88,;.93,-7.11,;2.39,-7.59,;3.3,-6.34,;2.39,-5.09,;.93,-5.57,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608870 (US11702409, Example 20a | US11702409, Example 20b) Show SMILES Cc1c(c(nn1C1CC2(C1)CN(C2)C(=O)C=C)-c1cnc(N)c(F)c1)-c1c(Cl)c(C)cc2[nH]ncc12 |(-3.12,-2.83,;-1.65,-2.36,;-.41,-3.26,;.84,-2.36,;.36,-.89,;-1.18,-.89,;-1.95,.44,;-3.43,.84,;-3.03,2.33,;-1.55,1.93,;-4.52,2.73,;-4.12,4.22,;-2.64,3.82,;-5.21,5.3,;-6.7,4.91,;-4.81,6.79,;-5.9,7.88,;2.31,-2.83,;3.45,-1.8,;4.91,-2.28,;5.23,-3.78,;6.7,-4.26,;4.09,-4.81,;4.41,-6.32,;2.63,-4.34,;-.41,-4.8,;-1.74,-5.57,;-3.07,-4.8,;-1.74,-7.11,;-3.07,-7.88,;-.41,-7.88,;.93,-7.11,;2.39,-7.59,;3.3,-6.34,;2.39,-5.09,;.93,-5.57,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair