null

SMILES: CC(=O)N1CCc2cc(ccc12)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608876 (US11702409, Example 22a | US11702409, Example 22b) Show SMILES CC(=O)N1CCc2cc(ccc12)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(7.89,-5.28,;6.35,-5.28,;5.58,-6.61,;5.58,-3.94,;6.2,-2.54,;5.06,-1.51,;3.73,-2.28,;2.26,-1.8,;1.12,-2.83,;1.44,-4.34,;2.9,-4.81,;4.05,-3.78,;-.35,-2.36,;-.82,-.89,;-2.36,-.89,;-3.13,.44,;-4.62,.84,;-4.22,2.33,;-2.73,1.93,;-5.71,2.73,;-5.31,4.22,;-3.82,3.82,;-6.4,5.3,;-7.89,4.91,;-6,6.79,;-7.09,7.88,;-2.84,-2.36,;-4.3,-2.83,;-1.59,-3.26,;-1.59,-4.8,;-2.93,-5.57,;-4.26,-4.8,;-2.93,-7.11,;-4.26,-7.88,;-1.59,-7.88,;-.26,-7.11,;1.2,-7.59,;2.11,-6.34,;1.2,-5.09,;-.26,-5.57,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608876 (US11702409, Example 22a | US11702409, Example 22b) Show SMILES CC(=O)N1CCc2cc(ccc12)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(7.89,-5.28,;6.35,-5.28,;5.58,-6.61,;5.58,-3.94,;6.2,-2.54,;5.06,-1.51,;3.73,-2.28,;2.26,-1.8,;1.12,-2.83,;1.44,-4.34,;2.9,-4.81,;4.05,-3.78,;-.35,-2.36,;-.82,-.89,;-2.36,-.89,;-3.13,.44,;-4.62,.84,;-4.22,2.33,;-2.73,1.93,;-5.71,2.73,;-5.31,4.22,;-3.82,3.82,;-6.4,5.3,;-7.89,4.91,;-6,6.79,;-7.09,7.88,;-2.84,-2.36,;-4.3,-2.83,;-1.59,-3.26,;-1.59,-4.8,;-2.93,-5.57,;-4.26,-4.8,;-2.93,-7.11,;-4.26,-7.88,;-1.59,-7.88,;-.26,-7.11,;1.2,-7.59,;2.11,-6.34,;1.2,-5.09,;-.26,-5.57,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair