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SMILES: COCCOCc1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 608933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608933 (US11702409, Example 39a | US11702409, Example 39b) Show SMILES COCCOCc1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(7.2,.03,;8.69,-.37,;9.09,-1.86,;8,-2.95,;6.51,-2.55,;5.42,-3.64,;3.94,-3.24,;2.79,-4.27,;1.33,-3.79,;1.01,-2.29,;2.15,-1.26,;3.61,-1.73,;-.46,-1.81,;-.93,-.35,;-2.47,-.35,;-3.24,.99,;-4.73,1.39,;-4.33,2.87,;-2.85,2.48,;-5.82,3.27,;-5.42,4.76,;-3.94,4.36,;-6.51,5.85,;-6.11,7.34,;-8,5.45,;-9.09,6.54,;-2.95,-1.81,;-4.42,-2.29,;-1.7,-2.72,;-1.7,-4.26,;-3.04,-5.03,;-4.37,-4.26,;-3.04,-6.57,;-4.37,-7.34,;-1.7,-7.34,;-.37,-6.57,;1.09,-7.04,;2,-5.8,;1.09,-4.55,;-.37,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair
GTPase KRas [G12C] (Homo sapiens (Human))	BDBM608933 (US11702409, Example 39a | US11702409, Example 39b) Show SMILES COCCOCc1ccc(cc1)-c1nn(C2CC3(C2)CN(C3)C(=O)C=C)c(C)c1-c1c(Cl)c(C)cc2[nH]ncc12 |(7.2,.03,;8.69,-.37,;9.09,-1.86,;8,-2.95,;6.51,-2.55,;5.42,-3.64,;3.94,-3.24,;2.79,-4.27,;1.33,-3.79,;1.01,-2.29,;2.15,-1.26,;3.61,-1.73,;-.46,-1.81,;-.93,-.35,;-2.47,-.35,;-3.24,.99,;-4.73,1.39,;-4.33,2.87,;-2.85,2.48,;-5.82,3.27,;-5.42,4.76,;-3.94,4.36,;-6.51,5.85,;-6.11,7.34,;-8,5.45,;-9.09,6.54,;-2.95,-1.81,;-4.42,-2.29,;-1.7,-2.72,;-1.7,-4.26,;-3.04,-5.03,;-4.37,-4.26,;-3.04,-6.57,;-4.37,-7.34,;-1.7,-7.34,;-.37,-6.57,;1.09,-7.04,;2,-5.8,;1.09,-4.55,;-.37,-5.03,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q20V8HXK
					More data for this Ligand-Target Pair