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SMILES: C[C@@H](Nc1nnc(C)c2cnc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(c1F)C(F)(F)F

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 609585   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Son of sevenless homolog 1 [564-1049]


()
BDBM609585
PNG
(US11702418, Example 12-60)
Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(c1F)C(F)(F)F |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
0.25n/an/an/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2C251J6
More data for this
Ligand-Target Pair
Son of sevenless homolog 1 [564-1049]


()
BDBM609585
PNG
(US11702418, Example 12-60)
Show SMILES C[C@@H](Nc1nnc(C)c2cnc(cc12)N1C[C@H]2CC[C@@H]1CN2C)c1cccc(c1F)C(F)(F)F |r,TLB:22:21:14.15:17.18,THB:11:14:21.20:17.18|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 24n/an/an/an/an/an/a


TBA



Citation and Details

BindingDB Entry DOI: 10.7270/Q2C251J6
More data for this
Ligand-Target Pair