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SMILES: COc1cnccc1NC(=O)c1ccc(o1)-c1c(ncn1C1CCOC1)-c1ccc(F)cc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 613867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM613867 (5-(4-(4-fluorophenyl)-1-(tetrahydrofuran-3-yl)-1H-...) Show SMILES COc1cnccc1NC(=O)c1ccc(o1)-c1c(ncn1C1CCOC1)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent									US Patent US11001589 (2021) BindingDB Entry DOI: 10.7270/Q2N30228
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM613867 (5-(4-(4-fluorophenyl)-1-(tetrahydrofuran-3-yl)-1H-...) Show SMILES COc1cnccc1NC(=O)c1ccc(o1)-c1c(ncn1C1CCOC1)-c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.21	n/a	n/a	n/a	n/a	n/a	n/a
ASTRAZENECA AB US Patent									US Patent US11001589 (2021) BindingDB Entry DOI: 10.7270/Q2N30228
					More data for this Ligand-Target Pair