BDBM61728 MLS000830182::N-(4-ketothieno[3,2-d][1,3]thiazin-2-yl)-2-furamide::N-(4-oxidanylidenethieno[3,2-d][1,3]thiazin-2-yl)furan-2-carboxamide::N-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-2-furancarboxamide::N-(4-oxo-4H-thieno[3,2-d][1,3]thiazin-2-yl)-2-furamide::N-(4-oxothieno[3,2-d][1,3]thiazin-2-yl)furan-2-carboxamide::SMR000458103::cid_2810061

SMILES: O=C(Nc1nc2ccsc2c(=O)s1)c1ccco1

InChI Key: InChIKey=VFHPAWYPWGGPTF-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 61728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human))	BDBM61728 (MLS000830182 | N-(4-ketothieno[3,2-d][1,3]thiazin-...) Show SMILES O=C(Nc1nc2ccsc2c(=O)s1)c1ccco1 Show InChI InChI=1S/C11H6N2O3S2/c14-9(7-2-1-4-16-7)13-11-12-6-3-5-17-8(6)10(15)18-11/h1-5H,(H,12,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PZ578V
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM61728 (MLS000830182 | N-(4-ketothieno[3,2-d][1,3]thiazin-...) Show SMILES O=C(Nc1nc2ccsc2c(=O)s1)c1ccco1 Show InChI InChI=1S/C11H6N2O3S2/c14-9(7-2-1-4-16-7)13-11-12-6-3-5-17-8(6)10(15)18-11/h1-5H,(H,12,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	2.28E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q29C6VXX
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM61728 (MLS000830182 | N-(4-ketothieno[3,2-d][1,3]thiazin-...) Show SMILES O=C(Nc1nc2ccsc2c(=O)s1)c1ccco1 Show InChI InChI=1S/C11H6N2O3S2/c14-9(7-2-1-4-16-7)13-11-12-6-3-5-17-8(6)10(15)18-11/h1-5H,(H,12,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2SB447H
					More data for this Ligand-Target Pair