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Enter Data

null

SMILES: CC(c1cnc(N2C[C@H]3C[C@H]3C2=O)c(C)c1)n1cc(NC(=O)c2cncc(n2)-c2c(F)c(Cl)ccc2C(F)F)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 617854
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM617854 (6-(3-Chloro-6-(difluoromethyl)-2-fluorophenyl)-N-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2DB8609
TBA					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM617854 (6-(3-Chloro-6-(difluoromethyl)-2-fluorophenyl)-N-(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2DB8609
TBA					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM617854 (6-(3-Chloro-6-(difluoromethyl)-2-fluorophenyl)-N-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2DB8609
TBA					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM617854 (6-(3-Chloro-6-(difluoromethyl)-2-fluorophenyl)-N-(...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2DB8609
TBA					More data for this Ligand-Target Pair