null

SMILES: CN1CCN(CCOc2ccc(-c3c(sc4ncnc(OC(Cc5ccccc5OCc5ccnn5CC(F)(F)F)C(O)=O)c34)-c3ccc(F)o3)c(C)c2Cl)CC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 618607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM618607 (US11760752, Compound S-63845) Show SMILES CN1CCN(CCOc2ccc(-c3c(sc4ncnc(OC(Cc5ccccc5OCc5ccnn5CC(F)(F)F)C(O)=O)c34)-c3ccc(F)o3)c(C)c2Cl)CC1 |(-7.79,-11.47,;-6.28,-11.15,;-5.25,-12.3,;-3.74,-11.98,;-3.27,-10.51,;-1.76,-10.19,;-1.28,-8.73,;.22,-8.41,;.7,-6.94,;2.2,-6.62,;2.68,-5.16,;1.65,-4.01,;2.13,-2.55,;1.22,-1.3,;2.13,-.06,;3.59,-.53,;4.92,.24,;6.26,-.53,;6.26,-2.07,;4.92,-2.84,;4.92,-4.38,;6.26,-5.15,;7.59,-4.38,;8.93,-5.15,;8.93,-6.69,;10.26,-7.46,;11.59,-6.69,;11.59,-5.15,;10.26,-4.38,;10.26,-2.84,;8.93,-2.07,;8.93,-.53,;7.68,.37,;8.16,1.84,;9.7,1.84,;10.17,.37,;11.64,-.1,;12.78,.93,;13.92,1.96,;13.81,-.22,;11.75,2.07,;6.26,-6.69,;4.92,-7.46,;7.59,-7.46,;3.59,-2.07,;-.32,-1.3,;-1.22,-2.55,;-2.69,-2.07,;-2.69,-.53,;-3.94,.37,;-1.22,-.06,;.14,-4.33,;-.89,-3.19,;-.33,-5.8,;-1.84,-6.12,;-4.3,-9.37,;-5.8,-9.69,)| Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair