BDBM61892 MLS001303550::N-(1,3-benzothiazol-2-yl)-2-[(3-cyano-5-hydroxy-7-keto-4H-thieno[3,2-b]pyridin-2-yl)thio]acetamide::N-(1,3-benzothiazol-2-yl)-2-[(3-cyano-5-hydroxy-7-oxo-4H-thieno[3,2-b]pyridin-2-yl)sulfanyl]acetamide::N-(1,3-benzothiazol-2-yl)-2-[(3-cyano-5-hydroxy-7-oxo-4H-thieno[3,2-b]pyridin-2-yl)thio]acetamide::N-(1,3-benzothiazol-2-yl)-2-[(3-cyano-5-oxidanyl-7-oxidanylidene-4H-thieno[3,2-b]pyridin-2-yl)sulfanyl]ethanamide::N-(1,3-benzothiazol-2-yl)-2-[(3-cyano-7-hydroxy-5-keto-4H-thieno[3,2-b]pyridin-2-yl)thio]acetamide::N-Benzothiazol-2-yl-2-(3-cyano-7-hydroxy-5-oxo-4,5-dihydro-thieno[3,2-b]pyridin-2-ylsulfanyl)-acetamide::SMR000606648::cid_6499473

SMILES: Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12

InChI Key: InChIKey=UZHXBLBWHKAGOE-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 61892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2J67FCM
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DF6PNW
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2X63KDM
					More data for this Ligand-Target Pair
Homo sapiens huntingtin (HTT), mRNA (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2H130G1
					More data for this Ligand-Target Pair
Alpi (Rattus norvegicus (Rat))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DB809V
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM61892 (MLS001303550 | N-(1,3-benzothiazol-2-yl)-2-[(3-cya...) Show SMILES Oc1cc(=O)[nH]c2c(C#N)c(SCC(=O)Nc3nc4ccccc4s3)sc12 Show InChI InChI=1S/C17H10N4O3S3/c18-6-8-14-15(10(22)5-12(23)20-14)27-16(8)25-7-13(24)21-17-19-9-3-1-2-4-11(9)26-17/h1-5H,7H2,(H,19,21,24)(H2,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2NS0SCW
					More data for this Ligand-Target Pair