Found 11 hits for monomerid = 621168 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.0850 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835H]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 (D835Y)
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [572-603]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [K663Q]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [N841I]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [R834Q]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V]
(Homo sapiens (Human)) | BDBM621168
(6-(6-(1-cyclopropyl-1H- pyrazol-4-yl)imidazo- [1,2...)Show SMILES F[C@H]1CNC[C@@H]1Nc1cccc(n1)-c1cnc2ccc(cn12)-c1cnn(c1)C1CC1 |r| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |