BindingDB logo
myBDB logout

null

SMILES: CNC(=O)OCC1CCN(Cc2cc(Oc3cnc(nc3)N3CCN(CC3)C3CC(C3)C(O)=O)nc(c2)-c2cc(Cl)cc(Cl)c2)CC1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 621459   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Furin [108-574]


(Homo sapiens (Human))		BDBM621459
PNG
(US11773078, Example 211)
Show SMILES CNC(=O)OCC1CCN(Cc2cc(Oc3cnc(nc3)N3CCN(CC3)C3CC(C3)C(O)=O)nc(c2)-c2cc(Cl)cc(Cl)c2)CC1 |(14.95,-1.31,;13.61,-2.08,;12.28,-1.31,;12.28,.23,;10.95,-2.08,;9.61,-1.31,;8.28,-2.08,;8.28,-3.62,;6.94,-4.39,;5.61,-3.62,;4.28,-4.39,;2.94,-3.62,;1.61,-4.39,;.28,-3.62,;-1.06,-4.39,;-2.39,-3.62,;-3.72,-4.39,;-5.06,-3.62,;-5.06,-2.08,;-3.72,-1.31,;-2.39,-2.08,;-6.39,-1.31,;-7.73,-2.08,;-9.06,-1.31,;-9.06,.23,;-7.73,1,;-6.39,.23,;-10.39,1,;-10.79,2.48,;-12.28,2.08,;-11.88,.6,;-13.61,2.85,;-14.95,2.08,;-13.61,4.39,;.28,-2.08,;1.61,-1.31,;2.94,-2.08,;1.61,.23,;.28,1,;.28,2.54,;-1.06,3.31,;1.61,3.31,;2.94,2.54,;4.28,3.31,;2.94,1,;5.61,-2.08,;6.94,-1.31,)|
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0790n/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair