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SMILES: C[C@@H]1N(C)c2nc(N[C@H]3C[C@@H](C3)OCc3cc(F)c(F)c(F)c3)nc(C)c2NC1=O

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622564   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))		BDBM622564
PNG
((7S)-4,7,8-trimethyl-2-((trans-3-((3,4,5-trifluoro...)
Show SMILES C[C@@H]1N(C)c2nc(N[C@H]3C[C@@H](C3)OCc3cc(F)c(F)c(F)c3)nc(C)c2NC1=O |wU:8.7,1.0,wD:10.12,(,-3.08,;1.33,-2.31,;2.67,-3.08,;2.67,-4.62,;4,-2.31,;5.33,-3.08,;6.67,-2.31,;8,-3.08,;8,-4.62,;9.09,-5.71,;8,-6.8,;6.91,-5.71,;8,-8.34,;9.34,-9.11,;9.34,-10.65,;10.67,-11.42,;10.67,-12.96,;12,-13.73,;9.34,-13.73,;9.34,-15.27,;8,-12.96,;6.67,-13.73,;8,-11.42,;6.67,-.77,;5.33,,;5.33,1.54,;4,-.77,;2.67,,;1.33,-.77,;)|
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
>4.00E+3n/an/an/an/an/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair