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SMILES: Cn1ccnc1C1CCCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1

InChI Key: InChIKey=ZVAQJLZGAVMXES-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 63389   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock factor protein 1


(Mus musculus)		BDBM63389
PNG
(1-({5-[(2-chloro-4-fluorophenoxy)methyl]isoxazol-3...)
Show SMILES Cn1ccnc1C1CCCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1
Show InChI InChI=1S/C20H20ClFN4O3/c1-25-9-7-23-19(25)17-4-2-3-8-26(17)20(27)16-11-14(29-24-16)12-28-18-6-5-13(22)10-15(18)21/h5-7,9-11,17H,2-4,8,12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>1.95E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2MW2FKX
More data for this
Ligand-Target Pair