null

SMILES: COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(Nc5nc(nc(N6CCS(=O)(=O)CC6)c5Cl)C(C)C)n[nH]c4c3)c2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 635953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PLK4 (Homo sapiens (Human))	BDBM635953 ((1R,2S)-2-(3-((5-chloro-6-(1,1-dioxidothiomorpholi...) Show SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(Nc5nc(nc(N6CCS(=O)(=O)CC6)c5Cl)C(C)C)n[nH]c4c3)c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM635953 ((1R,2S)-2-(3-((5-chloro-6-(1,1-dioxidothiomorpholi...) Show SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(Nc5nc(nc(N6CCS(=O)(=O)CC6)c5Cl)C(C)C)n[nH]c4c3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	623	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM635953 ((1R,2S)-2-(3-((5-chloro-6-(1,1-dioxidothiomorpholi...) Show SMILES COc1ccc2NC(=O)[C@@]3(C[C@H]3c3ccc4c(Nc5nc(nc(N6CCS(=O)(=O)CC6)c5Cl)C(C)C)n[nH]c4c3)c2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair