BDBM64181 4-(7-ethyl-1H-indol-3-yl)-N-(2-methoxyethyl)-1,3-thiazol-2-amine::4-(7-ethyl-1H-indol-3-yl)-N-(2-methoxyethyl)-2-thiazolamine::MLS001174721::SMR000591886::[4-(7-ethyl-1H-indol-3-yl)thiazol-2-yl]-(2-methoxyethyl)amine::cid_4826888

SMILES: CCc1cccc2c(c[nH]c12)-c1csc(NCCOC)n1

InChI Key: InChIKey=DBCHIJGLXLMNRL-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 64181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hsf1 protein (Mus musculus)	BDBM64181 (4-(7-ethyl-1H-indol-3-yl)-N-(2-methoxyethyl)-1,3-t...) Show SMILES CCc1cccc2c(c[nH]c12)-c1csc(NCCOC)n1 Show InChI InChI=1S/C16H19N3OS/c1-3-11-5-4-6-12-13(9-18-15(11)12)14-10-21-16(19-14)17-7-8-20-2/h4-6,9-10,18H,3,7-8H2,1-2H3,(H,17,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.95E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair
LARGE (Homo sapiens (Human))	BDBM64181 (4-(7-ethyl-1H-indol-3-yl)-N-(2-methoxyethyl)-1,3-t...) Show SMILES CCc1cccc2c(c[nH]c12)-c1csc(NCCOC)n1 Show InChI InChI=1S/C16H19N3OS/c1-3-11-5-4-6-12-13(9-18-15(11)12)14-10-21-16(19-14)17-7-8-20-2/h4-6,9-10,18H,3,7-8H2,1-2H3,(H,17,19)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.75E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VT1QQ4
					More data for this Ligand-Target Pair
LARGE (Homo sapiens (Human))	BDBM64181 (4-(7-ethyl-1H-indol-3-yl)-N-(2-methoxyethyl)-1,3-t...) Show SMILES CCc1cccc2c(c[nH]c12)-c1csc(NCCOC)n1 Show InChI InChI=1S/C16H19N3OS/c1-3-11-5-4-6-12-13(9-18-15(11)12)14-10-21-16(19-14)17-7-8-20-2/h4-6,9-10,18H,3,7-8H2,1-2H3,(H,17,19)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.88E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2833QM1
					More data for this Ligand-Target Pair