null

SMILES: C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@H]4CC[C@@H]5C[C@H](CCN45)C(=O)N(C)C)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)c(F)c(C)c1C(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 647901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase KRas [G12D] (Homo sapiens (Human))	BDBM647901 (US20240025919, Compound 133) Show SMILES C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@H]4CC[C@@H]5C[C@H](CCN45)C(=O)N(C)C)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)c(F)c(C)c1C(F)(F)F |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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GTPase KRas [G12D] (Homo sapiens (Human))	BDBM647901 (US20240025919, Compound 133) Show SMILES C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@H]4CC[C@@H]5C[C@H](CCN45)C(=O)N(C)C)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)c(F)c(C)c1C(F)(F)F |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GTPase KRas [G12D] (Homo sapiens (Human))	BDBM647901 (US20240025919, Compound 133) Show SMILES C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@H]4CC[C@@H]5C[C@H](CCN45)C(=O)N(C)C)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)c(F)c(C)c1C(F)(F)F |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
GTPase KRas [G12D] (Homo sapiens (Human))	BDBM647901 (US20240025919, Compound 133) Show SMILES C[C@@H]1Oc2nc(c(F)c3nc(OC[C@@H]4CC[C@@H]5C[C@H](CCN45)C(=O)N(C)C)nc(N4C[C@H]5CC[C@H](N5)[C@@H]14)c23)-c1cc(N)c(F)c(C)c1C(F)(F)F |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair