Found 7 hits for monomerid = 648232 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
DNA-dependent protein kinase catalytic subunit
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK1
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Aurora kinase B
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase JAK2
(Homo sapiens (Human)) | BDBM648232
(US11884671, Example 9)Show SMILES COc1ccnc2cc(C)c(Nc3ncc4n(C)c(=O)n([C@H]5CC[C@H](O)CC5)c4n3)cc12 |r,wU:24.24,wD:21.20,(2.01,2.74,;2.01,1.2,;3.34,.43,;4.68,1.2,;6.01,.43,;6.01,-1.11,;4.68,-1.88,;4.68,-3.42,;3.34,-4.19,;3.34,-5.73,;2.01,-3.42,;.68,-4.19,;-.66,-3.42,;-1.99,-4.19,;-3.33,-3.42,;-3.33,-1.88,;-4.47,-.85,;-6.01,-.85,;-3.84,.56,;-4.61,1.89,;-2.31,.4,;-1.54,1.73,;-0,1.73,;.77,3.06,;-0,4.4,;.77,5.73,;-1.54,4.4,;-2.31,3.06,;-1.99,-1.11,;-.66,-1.88,;2.01,-1.88,;3.34,-1.11,)| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Search and Browse
