BDBM65521 (S)-4-(3-(2-(benzylamino)-2-oxo-1-phenylethyl)ureido)-N-(6-(hydroxyamino)-6-oxohexyl)benzamide (L1)

SMILES: ONC(=O)CCCCCNC(=O)c1ccc(NC(=O)N[C@H](C(=O)NCc2ccccc2)c2ccccc2)cc1

InChI Key: InChIKey=OGRLCQLFLZQCEH-SANMLTNESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM65521 ((S)-4-(3-(2-(benzylamino)-2-oxo-1-phenylethyl)urei...) Show SMILES ONC(=O)CCCCCNC(=O)c1ccc(NC(=O)N[C@H](C(=O)NCc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C29H33N5O5/c35-25(34-39)14-8-3-9-19-30-27(36)23-15-17-24(18-16-23)32-29(38)33-26(22-12-6-2-7-13-22)28(37)31-20-21-10-4-1-5-11-21/h1-2,4-7,10-13,15-18,26,39H,3,8-9,14,19-20H2,(H,30,36)(H,31,37)(H,34,35)(H2,32,33,38)/t26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qingdao University					Assay Description The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...				J Enzyme Inhib Med Chem 29: 582-9 (2014) Article DOI: 10.3109/14756366.2013.827678 BindingDB Entry DOI: 10.7270/Q2S46Q3F
					More data for this Ligand-Target Pair