BDBM65526 (S)-4-(3-(2-((4-(tert-butyl)phenyl)amino)-2-oxo-1-phenylethyl)ureido)-N-(6-(hydroxyamino)-6-oxohexyl)benzamide (L4)

SMILES: CC(C)(C)c1ccc(NC(=O)[C@@H](NC(=O)Nc2ccc(cc2)C(=O)NCCCCCC(=O)NO)c2ccccc2)cc1

InChI Key: InChIKey=ZNWLNMVFKWPVGB-NDEPHWFRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM65526 ((S)-4-(3-(2-((4-(tert-butyl)phenyl)amino)-2-oxo-1-...) Show SMILES CC(C)(C)c1ccc(NC(=O)[C@@H](NC(=O)Nc2ccc(cc2)C(=O)NCCCCCC(=O)NO)c2ccccc2)cc1 Show InChI InChI=1S/C32H39N5O5/c1-32(2,3)24-15-19-25(20-16-24)34-30(40)28(22-10-6-4-7-11-22)36-31(41)35-26-17-13-23(14-18-26)29(39)33-21-9-5-8-12-27(38)37-42/h4,6-7,10-11,13-20,28,42H,5,8-9,12,21H2,1-3H3,(H,33,39)(H,34,40)(H,37,38)(H2,35,36,41)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qingdao University					Assay Description The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...				J Enzyme Inhib Med Chem 29: 582-9 (2014) Article DOI: 10.3109/14756366.2013.827678 BindingDB Entry DOI: 10.7270/Q2S46Q3F
					More data for this Ligand-Target Pair