BDBM6597 2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(thiophen-2-yl)acetate::Bis(1H-2-indolyl)methanone deriv. 55

SMILES: O=C(Cc1cccs1)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1

InChI Key: InChIKey=XTOWMFGOCVBOQW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6597 (2-(1H-indol-2-ylcarbonyl)-1H-indol-5-yl 2-(thiophe...) Show SMILES O=C(Cc1cccs1)Oc1ccc2[nH]c(cc2c1)C(=O)c1cc2ccccc2[nH]1 Show InChI InChI=1S/C23H16N2O3S/c26-22(13-17-5-3-9-29-17)28-16-7-8-19-15(10-16)12-21(25-19)23(27)20-11-14-4-1-2-6-18(14)24-20/h1-12,24-25H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of Regensburg					Assay Description The cells were stimulated with PDGF (100 ng/mL) for 10 min at room temperature. Then the cell lysates were analyzed by SDS-PAGE and immunoblotting wi...				J Med Chem 45: 1002-18 (2002) Article DOI: 10.1021/jm010988n BindingDB Entry DOI: 10.7270/Q2GM85H0
					More data for this Ligand-Target Pair