BDBM66270 3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide::3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)coumarilamide::3-(cyclopropylcarbonylamino)-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide::3-[(cyclopropylcarbonyl)amino]-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide::3-[[cyclopropyl(oxo)methyl]amino]-N-(4-methoxyphenyl)-2-benzofurancarboxamide::MLS000092988::SMR000028624::cid_3243757
SMILES: COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C2CC2)cc1
InChI Key: InChIKey=NXOFLKSZXPKUKS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Bcl-2-like protein 11 (Homo sapiens (Human)) | BDBM66270![]() (3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >3.50E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...) | BDBM66270![]() (3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q29W0D3P | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...) | BDBM66270![]() (3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FN14T0 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...) | BDBM66270![]() (3-(cyclopropanecarbonylamino)-N-(4-methoxyphenyl)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KD1WJB | ||||||||||||
More data for this Ligand-Target Pair |