BDBM66978 (E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine;hydrate;hydrochloride::(E)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-3-yl-prop-2-en-1-amine;hydrate;hydrochloride::(E)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-3-ylprop-2-en-1-amine;hydrate;hydrochloride::MLS002154197::SMR001233484::Zimelidine (E-isomer)::Zimelidine (Z-isomer)::Zimelidine dihydrochloride monohydrate::[(E)-3-(4-bromophenyl)-3-(3-pyridyl)allyl]-dimethyl-amine;hydrate;hydrochloride::cid_24871308

SMILES: CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1

InChI Key: InChIKey=OYPPVKRFBIWMSX-CXUHLZMHSA-N

Data: 2 KI  2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 66978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM66978 ((E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)...) Show SMILES CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	77.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Administration Medical Center Curated by PDSP Ki Database									Brain Res 454: 78-88 (1988) Article DOI: 10.1016/0006-8993(88)90805-0 BindingDB Entry DOI: 10.7270/Q28914C5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM66978 ((E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)...) Show SMILES CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Administration Medical Center Curated by PDSP Ki Database									Brain Res 454: 78-88 (1988) Article DOI: 10.1016/0006-8993(88)90805-0 BindingDB Entry DOI: 10.7270/Q28914C5
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM66978 ((E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)...) Show SMILES CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of accumulation of [14C]-5-HT (5-HT) in mouse brain slices				J Med Chem 24: 1499-507 (1982) BindingDB Entry DOI: 10.7270/Q2BG2N05
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM66978 ((E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)...) Show SMILES CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of accumulation of (-)-[3H]-Norepinephrine (NA) in mouse brain slices				J Med Chem 24: 1499-507 (1982) BindingDB Entry DOI: 10.7270/Q2BG2N05
					More data for this Ligand-Target Pair
Bcl-2-like protein 11 (Homo sapiens (Human))	BDBM66978 ((E)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)...) Show SMILES CN(C)C\C=C(/c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C16H17BrN2/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13/h3-10,12H,11H2,1-2H3/b16-9+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ
					More data for this Ligand-Target Pair