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SMILES: COc1cc2cnc(-c3ccccc3)c(-c3cccc(c3)C(F)(F)F)c2cc1OC

InChI Key: InChIKey=NOPDHOZGIJMWDL-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67032   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens (Human))		BDBM67032
PNG
(6,7-dimethoxy-3-phenyl-4-[3-(trifluoromethyl)pheny...)
Show SMILES COc1cc2cnc(-c3ccccc3)c(-c3cccc(c3)C(F)(F)F)c2cc1OC
Show InChI InChI=1S/C24H18F3NO2/c1-29-20-12-17-14-28-23(15-7-4-3-5-8-15)22(19(17)13-21(20)30-2)16-9-6-10-18(11-16)24(25,26)27/h3-14H,1-2H3
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KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair