BDBM6713 24-[(1-methyl-1H-imidazole-4-)sulfonyl]-1,4,14,24-tetraazaheptacyclo[16.8.1.0^{2,17}.0^{3,11}.0^{5,10}.0^{12,16}.0^{22,27}]heptacosa-2(17),3(11),5(10),6,8,12(16),18(27),19,21-nonaene-13,15-dione::aza-1,7-annulated indole deriv. 13b

SMILES: Cn1cnc(c1)S(=O)(=O)N1CCn2c3c(C1)cccc3c1c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c21

InChI Key: InChIKey=IPADIYGARMXRRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-Dependent Protein Kinase (PKA) (Bos taurus (bovine))	BDBM6713 (24-[(1-methyl-1H-imidazole-4-)sulfonyl]-1,4,14,24-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CCn2c3c(C1)cccc3c1c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c21 Show InChI InChI=1S/C27H20N6O4S/c1-31-12-18(28-13-31)38(36,37)32-9-10-33-24-14(11-32)5-4-7-16(24)20-22-21(26(34)30-27(22)35)19-15-6-2-3-8-17(15)29-23(19)25(20)33/h2-8,12-13,29H,9-11H2,1H3,(H,30,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	25
Lilly Research Laboratories					Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]A...				Bioorg Med Chem Lett 14: 3925-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.088 BindingDB Entry DOI: 10.7270/Q2TX3CKP
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM6713 (24-[(1-methyl-1H-imidazole-4-)sulfonyl]-1,4,14,24-...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1CCn2c3c(C1)cccc3c1c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c21 Show InChI InChI=1S/C27H20N6O4S/c1-31-12-18(28-13-31)38(36,37)32-9-10-33-24-14(11-32)5-4-7-16(24)20-22-21(26(34)30-27(22)35)19-15-6-2-3-8-17(15)29-23(19)25(20)33/h2-8,12-13,29H,9-11H2,1H3,(H,30,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	7.0	22
Lilly Research Laboratories					Assay Description In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....				Bioorg Med Chem Lett 14: 3925-8 (2004) Article DOI: 10.1016/j.bmcl.2004.05.088 BindingDB Entry DOI: 10.7270/Q2TX3CKP
					More data for this Ligand-Target Pair