BDBM67398 5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl-3-pyrazolamine::5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl-pyrazol-3-amine::5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonylpyrazol-3-amine::MLS-0067132.0001::[5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl-pyrazol-3-yl]amine::cid_9551529

SMILES: COc1ccc(cc1OC)-c1cc(N)n(n1)S(=O)(=O)c1ccc(F)cc1

InChI Key: InChIKey=DGFAATACAXDBFQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 67398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM67398 (5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl...) Show SMILES COc1ccc(cc1OC)-c1cc(N)n(n1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H16FN3O4S/c1-24-15-8-3-11(9-16(15)25-2)14-10-17(19)21(20-14)26(22,23)13-6-4-12(18)5-7-13/h3-10H,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23J3BDQ
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM67398 (5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl...) Show SMILES COc1ccc(cc1OC)-c1cc(N)n(n1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H16FN3O4S/c1-24-15-8-3-11(9-16(15)25-2)14-10-17(19)21(20-14)26(22,23)13-6-4-12(18)5-7-13/h3-10H,19H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2V1237V
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM67398 (5-(3,4-dimethoxyphenyl)-2-(4-fluorophenyl)sulfonyl...) Show SMILES COc1ccc(cc1OC)-c1cc(N)n(n1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C17H16FN3O4S/c1-24-15-8-3-11(9-16(15)25-2)14-10-17(19)21(20-14)26(22,23)13-6-4-12(18)5-7-13/h3-10H,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZS2TX1
					More data for this Ligand-Target Pair