BDBM69209 MLS000706310::N-[4-methyl-6-(1-oxopentylamino)-3-pyridinyl]-2-thiophenecarboxamide::N-[4-methyl-6-(pentanoylamino)pyridin-3-yl]thiophene-2-carboxamide::N-[4-methyl-6-(valerylamino)-3-pyridyl]thiophene-2-carboxamide::SMR000288362::cid_3213152
SMILES: CCCCC(=O)Nc1cc(C)c(NC(=O)c2cccs2)cn1
InChI Key: InChIKey=JHQYZSSNCKRLGW-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM69209 (MLS000706310 | N-[4-methyl-6-(1-oxopentylamino)-3-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TX3CTT | |||||||||||
More data for this Ligand-Target Pair |