BDBM7351 6-(4-Chlorophenyl)[5H]pyrrolo[2,3-b]pyrazine::6-(4-chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 19

SMILES: Clc1ccc(cc1)-c1cc2nccnc2[nH]1

InChI Key: InChIKey=VFKHBJJSGUYSDC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 1 (CDK1) (Marthasterias glacialis (starfish))	BDBM7351 (6-(4-Chlorophenyl)[5H]pyrrolo[2,3-b]pyrazine | 6-(...) Show SMILES Clc1ccc(cc1)-c1cc2nccnc2[nH]1 Show InChI InChI=1S/C12H8ClN3/c13-9-3-1-8(2-4-9)10-7-11-12(16-10)15-6-5-14-11/h1-7H,(H,15,16)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.2	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
					More data for this Ligand-Target Pair