BDBM7568 (2E)-3-(2-hydroxyphenyl)prop-2-enal::Cinnamaldehyde deriv. IIa

SMILES: Oc1ccccc1\C=C\C=O

InChI Key: InChIKey=BSDNZCQPDVTDET-HWKANZROSA-N

Data: 4 IC50

PDB links: 6 PDB IDs contain this monomer as substructures. 13 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 1 (CDK1) (Marthasterias glacialis (starfish))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
					More data for this Ligand-Target Pair
Xanthine dehydrogenase (Homo sapiens (Human))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Medicinal Materials Curated by ChEMBL					Assay Description Inhibition of xanthine oxidase- mediated uric acid formation after 5 mins by spectrophotometry				Bioorg Med Chem Lett 22: 4625-8 (2012) Article DOI: 10.1016/j.bmcl.2012.05.051 BindingDB Entry DOI: 10.7270/Q2S46VVZ
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 10 mins by spectrophotometry				J Nat Prod 72: 1205-8 (2009) Article DOI: 10.1021/np900031q BindingDB Entry DOI: 10.7270/Q2QF8T0K
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM7568 ((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...) Show SMILES Oc1ccccc1\C=C\C=O Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	7.2	30
Korea Research Institute of Bioscience and Biotechnology					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3...				Bioorg Med Chem Lett 10: 1819-22 (2000) Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ
					More data for this Ligand-Target Pair