BDBM75910 5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinecarboxylic acid methyl ester::6-keto-5-(4-methoxyphenoxy)-1-p-cumenyl-pyridazine-4-carboxylic acid methyl ester::SR-02000000434::SR-02000000434-1::cid_46835813::methyl 5-(4-methoxyphenoxy)-6-oxidanylidene-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylate::methyl 5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylate
SMILES: COC(=O)c1cnn(-c2ccc(cc2)C(C)C)c(=O)c1Oc1ccc(OC)cc1
InChI Key: InChIKey=OJNYYBUWIWRUKR-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human)) | BDBM75910 (5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M32T72 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptides B/W receptor type 1 (Homo sapiens (Human)) | BDBM75910 (5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Curated by ChEMBL | Assay Description Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assay | Bioorg Med Chem Lett 22: 7135-41 (2012) Article DOI: 10.1016/j.bmcl.2012.09.074 BindingDB Entry DOI: 10.7270/Q2WS8VDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptides B/W receptor type 1 (Homo sapiens (Human)) | BDBM75910 (5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2GB22HQ | |||||||||||
More data for this Ligand-Target Pair |