BDBM76592 2-((E)-2-p-Tolyl-vinyl)-3H-quinazolin-4-one::2-[(E)-2-(4-methylphenyl)ethenyl]-1H-quinazolin-4-one::2-[(E)-2-(p-tolyl)vinyl]-1H-quinazolin-4-one::MLS000778154::SMR000414549::cid_5912184

SMILES: Cc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1

InChI Key: InChIKey=MBJSUONJTWIBKH-ZHACJKMWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 76592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-3 (Homo sapiens (Human))	BDBM76592 (2-((E)-2-p-Tolyl-vinyl)-3H-quinazolin-4-one | 2-[(...) Show SMILES Cc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1 |w:6.6| Show InChI InChI=1S/C17H14N2O/c1-12-6-8-13(9-7-12)10-11-16-18-15-5-3-2-4-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	999	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2RJ4GZT
					More data for this Ligand-Target Pair
SUMO-1-specific protease (Homo sapiens (Human))	BDBM76592 (2-((E)-2-p-Tolyl-vinyl)-3H-quinazolin-4-one | 2-[(...) Show SMILES Cc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1 |w:6.6| Show InChI InChI=1S/C17H14N2O/c1-12-6-8-13(9-7-12)10-11-16-18-15-5-3-2-4-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20)/b11-10+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	961	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27H1H10
					More data for this Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human))	BDBM76592 (2-((E)-2-p-Tolyl-vinyl)-3H-quinazolin-4-one | 2-[(...) Show SMILES Cc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1 |w:6.6| Show InChI InChI=1S/C17H14N2O/c1-12-6-8-13(9-7-12)10-11-16-18-15-5-3-2-4-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20)/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	403	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2C827R9
					More data for this Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human))	BDBM76592 (2-((E)-2-p-Tolyl-vinyl)-3H-quinazolin-4-one | 2-[(...) Show SMILES Cc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1 |w:6.6| Show InChI InChI=1S/C17H14N2O/c1-12-6-8-13(9-7-12)10-11-16-18-15-5-3-2-4-14(15)17(20)19-16/h2-11H,1H3,(H,18,19,20)/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MS3R7H
					More data for this Ligand-Target Pair