BDBM81786 5'-Methylthio Adenosine::5'-Methylthioado
SMILES: CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12
InChI Key: InChIKey=IRSFOARXPSIPGE-XNIJJKJLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Binding affinity against adenosine A1 receptor using [3H]DPCPX in rat cortical membranes in the absence of GTP | J Med Chem 41: 102-8 (1998) Article DOI: 10.1021/jm970508l BindingDB Entry DOI: 10.7270/Q2MK6DKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Binding affinity against adenosine A1 receptor using [3H]DPCPX in rat cortical membranes in the presence of GTP. | J Med Chem 41: 102-8 (1998) Article DOI: 10.1021/jm970508l BindingDB Entry DOI: 10.7270/Q2MK6DKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 243 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by PDSP Ki Database | Biochem Pharmacol 43: 1089-93 (1992) Article DOI: 10.1016/0006-2952(92)90616-q BindingDB Entry DOI: 10.7270/Q20863S6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Diabetes and Digestive and Kidney Diseases Curated by PDSP Ki Database | Biochem Pharmacol 43: 1089-93 (1992) Article DOI: 10.1016/0006-2952(92)90616-q BindingDB Entry DOI: 10.7270/Q20863S6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Binding affinity against Adenosine A2A receptor using [3H]-CGS- 21680 as the radioligand in rat striatal membranes | J Med Chem 41: 102-8 (1998) Article DOI: 10.1021/jm970508l BindingDB Entry DOI: 10.7270/Q2MK6DKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM81786![]() (5'-Methylthio Adenosine | 5'-Methylthioado) | PDB Reactome pathway KEGG GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 99 | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranes | J Med Chem 41: 102-8 (1998) Article DOI: 10.1021/jm970508l BindingDB Entry DOI: 10.7270/Q2MK6DKX | |||||||||||
More data for this Ligand-Target Pair |