BDBM83920 MLS000710056::N'-(2,6-dipiperidinopyrimidin-4-yl)-3-phenyl-propionohydrazide::N'-[2,6-bis(1-piperidinyl)-4-pyrimidinyl]-3-phenylpropanehydrazide::N'-[2,6-di(piperidin-1-yl)pyrimidin-4-yl]-3-phenyl-propanehydrazide::N'-[2,6-di(piperidin-1-yl)pyrimidin-4-yl]-3-phenylpropanehydrazide::SMR000291590::cid_1109397

SMILES: O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1

InChI Key: InChIKey=JZRIETCEGKDUCH-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 83920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-9 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	3.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25M647F
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2JM2870
					More data for this Ligand-Target Pair
Caspase-3 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2930RSV
					More data for this Ligand-Target Pair
SUMO/sentrin specific peptidase family member 8 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2P849HJ
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM83920 (MLS000710056 | N'-(2,6-dipiperidinopyrimidin-4-yl)...) Show SMILES O=C(CCc1ccccc1)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 Show InChI InChI=1S/C23H32N6O/c30-22(13-12-19-10-4-1-5-11-19)27-26-20-18-21(28-14-6-2-7-15-28)25-23(24-20)29-16-8-3-9-17-29/h1,4-5,10-11,18H,2-3,6-9,12-17H2,(H,27,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair