BDBM84517 Sulindac analogue, 14

SMILES: CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccoc1

InChI Key: InChIKey=XJUITJZJIVLMIP-NSIKDUERSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84517 (Sulindac analogue, 14) Show SMILES CC1=C(CC(O)=O)c2cc(F)ccc2\C1=C/c1ccoc1 |c:1| Show InChI InChI=1S/C17H13FO3/c1-10-14(6-11-4-5-21-9-11)13-3-2-12(18)7-16(13)15(10)8-17(19)20/h2-7,9H,8H2,1H3,(H,19,20)/b14-6-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institut für Molekulare Physiologie					Assay Description The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...				Chembiochem 6: 527-31 (2005) Article DOI: 10.1002/cbic.200400192 BindingDB Entry DOI: 10.7270/Q2KP80PS
					More data for this Ligand-Target Pair