BDBM84526 Sulindac analogue, 23

SMILES: CCC1=C(CC(O)=O)c2cc(\C=C\C(=O)OC(C)(C)C)ccc2\C1=C/c1ccsc1

InChI Key: InChIKey=ZCJSQTWKPMWGNT-JERDJRHPSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM84526 (Sulindac analogue, 23) Show SMILES CCC1=C(CC(O)=O)c2cc(\C=C\C(=O)OC(C)(C)C)ccc2\C1=C/c1ccsc1 |c:2| Show InChI InChI=1S/C25H26O4S/c1-5-18-20(13-17-10-11-30-15-17)19-8-6-16(7-9-24(28)29-25(2,3)4)12-21(19)22(18)14-23(26)27/h6-13,15H,5,14H2,1-4H3,(H,26,27)/b9-7+,20-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institut für Molekulare Physiologie					Assay Description The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...				Chembiochem 6: 527-31 (2005) Article DOI: 10.1002/cbic.200400192 BindingDB Entry DOI: 10.7270/Q2KP80PS
					More data for this Ligand-Target Pair