BDBM8763 1,2,3,4-Tetrahydropyrido[3,4-b]indole 8::methyl 2-{2-[(4-hydroxyphenyl)carbonyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indol-9-yl}acetate

SMILES: COC(=O)Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1

InChI Key: InChIKey=SXMHDYRUGCLEBU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-ACP Reductase (FabI) (Escherichia coli)	BDBM8763 (1,2,3,4-Tetrahydropyrido[3,4-b]indole 8 | methyl 2...) Show SMILES COC(=O)Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C21H20N2O4/c1-27-20(25)13-23-18-5-3-2-4-16(18)17-10-11-22(12-19(17)23)21(26)14-6-8-15(24)9-7-14/h2-9,24H,10-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.49E+4	n/a	n/a	n/a	n/a	n/a	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2241-4 (2001) Article DOI: 10.1016/s0960-894x(01)00405-x BindingDB Entry DOI: 10.7270/Q24X5610
					More data for this Ligand-Target Pair
Enoyl-ACP Reductase (FabI) (Staphylococcus aureus)	BDBM8763 (1,2,3,4-Tetrahydropyrido[3,4-b]indole 8 | methyl 2...) Show SMILES COC(=O)Cn1c2CN(CCc2c2ccccc12)C(=O)c1ccc(O)cc1 Show InChI InChI=1S/C21H20N2O4/c1-27-20(25)13-23-18-5-3-2-4-16(18)17-10-11-22(12-19(17)23)21(26)14-6-8-15(24)9-7-14/h2-9,24H,10-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	6.5	30
GlaxoSmithKline					Assay Description Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...				Bioorg Med Chem Lett 11: 2241-4 (2001) Article DOI: 10.1016/s0960-894x(01)00405-x BindingDB Entry DOI: 10.7270/Q24X5610
					More data for this Ligand-Target Pair