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SMILES: O[C@@H](C[C@@H](Cc1ccc(OCCOC(=O)N2CCOCC2)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)CN1[C@@H](Cc2ccccc2)C[C@H](Cc2ccccc2)C1=O

InChI Key: InChIKey=FKLCRUVOWWCXRT-HYESOODXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9196   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A]


(Human immunodeficiency virus type 1)		BDBM9196
PNG
(2-{4-[(2R)-2-[(2S)-3-[(3S,5R)-3,5-dibenzyl-2-oxopy...)
Show SMILES O[C@@H](C[C@@H](Cc1ccc(OCCOC(=O)N2CCOCC2)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)CN1[C@@H](Cc2ccccc2)C[C@H](Cc2ccccc2)C1=O |r|
Show InChI InChI=1S/C46H53N3O8/c50-39(31-49-38(27-33-11-5-2-6-12-33)28-37(45(49)53)26-32-9-3-1-4-10-32)29-36(44(52)47-43-41-14-8-7-13-35(41)30-42(43)51)25-34-15-17-40(18-16-34)56-23-24-57-46(54)48-19-21-55-22-20-48/h1-18,36-39,42-43,50-51H,19-31H2,(H,47,52)/t36-,37+,38+,39+,42-,43+/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.0500 -14.0 240n/an/an/an/a6.425



GlaxoSmithKline



Assay Description
The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...

Bioorg Med Chem Lett 15: 81-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.10.029
BindingDB Entry DOI: 10.7270/Q29G5K1M
More data for this
Ligand-Target Pair