BDBM93437 Flavonid, 6b

SMILES: COc1cccc(Cl)c1-c1cc(=O)c2ccc(F)cc2o1

InChI Key: InChIKey=ZLFOHYSJKJHFCW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 93437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin L2 (Homo sapiens (Human))	BDBM93437 (Flavonid, 6b) Show SMILES COc1cccc(Cl)c1-c1cc(=O)c2ccc(F)cc2o1 Show InChI InChI=1S/C16H10ClFO3/c1-20-13-4-2-3-11(17)16(13)15-8-12(19)10-6-5-9(18)7-14(10)21-15/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	5.5	27
Universidade Federal de São Carlo					Assay Description Recombinant human cathepsin V was expressed and purified as described previously.				J Comb Chem 12: 687-95 (2010) Article DOI: 10.1021/cc100076k BindingDB Entry DOI: 10.7270/Q269726R
					More data for this Ligand-Target Pair