BDBM97481 US8470816, 265
SMILES: CN([C@@H]1CCN(C[C@H]1c1ccc(Cl)c(Cl)c1)C(=O)C1CCN(CC1)C(C)=O)C(=O)c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=LQRMREXDSWNGEJ-WIOPSUGQSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurokinin 2 receptor (Homo sapiens (Human)) | BDBM97481![]() (US8470816, 265) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors. | US Patent US8470816 (2013) BindingDB Entry DOI: 10.7270/Q2NZ8688 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurokinin 1 receptor (Homo sapiens (Human)) | BDBM97481![]() (US8470816, 265) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 80 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description Radioligan receptor binding inhibitory activity using membrane fraction of CHO cell expressing human NK receptors. | US Patent US8470816 (2013) BindingDB Entry DOI: 10.7270/Q2NZ8688 | |||||||||||
More data for this Ligand-Target Pair |