BDBM97514 US8470820, 25
SMILES: OCCn1nc(cc1NC(=O)c1nc(ccc1Nc1cncnc1)C1CC1)-c1ccc2ccccc2n1
InChI Key: InChIKey=YNAXKEZCEMCSCE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human)) | BDBM97514 (US8470820, 25) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Hoffman-La Roche Inc. US Patent | Assay Description Scintillation proximity assay using human PDE10A. | US Patent US8470820 (2013) BindingDB Entry DOI: 10.7270/Q2J96501 | |||||||||||
More data for this Ligand-Target Pair |