BDBM97521 US8470820, 32

SMILES: O=C(Nc1cc(nn1CC1CCCCC1)-c1ccccn1)c1nc(ccc1Nc1cncnc1)C1CC1

InChI Key: InChIKey=QOVYJVGYKTUQJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM97521 (US8470820, 32) Show SMILES O=C(Nc1cc(nn1CC1CCCCC1)-c1ccccn1)c1nc(ccc1Nc1cncnc1)C1CC1 Show InChI InChI=1S/C28H30N8O/c37-28(27-24(32-21-15-29-18-30-16-21)12-11-22(33-27)20-9-10-20)34-26-14-25(23-8-4-5-13-31-23)35-36(26)17-19-6-2-1-3-7-19/h4-5,8,11-16,18-20,32H,1-3,6-7,9-10,17H2,(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Hoffman-La Roche Inc. US Patent					Assay Description Scintillation proximity assay using human PDE10A.				US Patent US8470820 (2013) BindingDB Entry DOI: 10.7270/Q2J96501
					More data for this Ligand-Target Pair