null
SMILES: OC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C2CC3CCCC(C3)C2)c1=O
InChI Key: InChIKey=WKPMMJFYKKQWLO-WZMLIQCHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM97716 (US8476271, 97) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 203 | -9.12 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P.; Shionogi & Co., Ltd. US Patent | Assay Description In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. | US Patent US8476271 (2013) BindingDB Entry DOI: 10.7270/Q2416VNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM97716 (US8476271, 97) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.69E+3 | -7.59 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P.; Shionogi & Co., Ltd. US Patent | Assay Description In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. | US Patent US8476271 (2013) BindingDB Entry DOI: 10.7270/Q2416VNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97716 (US8476271, 97) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.83E+3 | -7.39 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P.; Shionogi & Co., Ltd. US Patent | Assay Description In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. | US Patent US8476271 (2013) BindingDB Entry DOI: 10.7270/Q2416VNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM97716 (US8476271, 97) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >2.00E+4 | >-6.41 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P.; Shionogi & Co., Ltd. US Patent | Assay Description In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. | US Patent US8476271 (2013) BindingDB Entry DOI: 10.7270/Q2416VNB | |||||||||||
More data for this Ligand-Target Pair |