null

SMILES: Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(o3)C(=O)NCCN3CCCC3)nnc2c1

InChI Key: InChIKey=NDUAHACMVSARNG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 97860   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM97860 (US8481536, 407 | US8481536, 587) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(o3)C(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H30N6O2/c1-17-7-6-8-18(2)24(17)20-15-19(3)25-21(16-20)31-32-27(30-25)29-23-10-9-22(35-23)26(34)28-11-14-33-12-4-5-13-33/h6-10,15-16H,4-5,11-14H2,1-3H3,(H,28,34)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM97860 (US8481536, 407 | US8481536, 587) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(o3)C(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H30N6O2/c1-17-7-6-8-18(2)24(17)20-15-19(3)25-21(16-20)31-32-27(30-25)29-23-10-9-22(35-23)26(34)28-11-14-33-12-4-5-13-33/h6-10,15-16H,4-5,11-14H2,1-3H3,(H,28,34)(H,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	68.7	n/a	n/a	n/a	n/a	n/a	37
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM97860 (US8481536, 407 | US8481536, 587) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(o3)C(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H30N6O2/c1-17-7-6-8-18(2)24(17)20-15-19(3)25-21(16-20)31-32-27(30-25)29-23-10-9-22(35-23)26(34)28-11-14-33-12-4-5-13-33/h6-10,15-16H,4-5,11-14H2,1-3H3,(H,28,34)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Homo sapiens (Human))	BDBM97860 (US8481536, 407 | US8481536, 587) Show SMILES Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(o3)C(=O)NCCN3CCCC3)nnc2c1 Show InChI InChI=1S/C27H30N6O2/c1-17-7-6-8-18(2)24(17)20-15-19(3)25-21(16-20)31-32-27(30-25)29-23-10-9-22(35-23)26(34)28-11-14-33-12-4-5-13-33/h6-10,15-16H,4-5,11-14H2,1-3H3,(H,28,34)(H,29,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18.3	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair