BDBM98257 US8481733, 69

SMILES: Nc1nccn2c(nc(-c3ccc(cc3Cl)C(=O)c3ccccc3)c12)C1CCC1

InChI Key: InChIKey=VETRLGPHIGQYQX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM98257 (US8481733, 69) Show SMILES Nc1nccn2c(nc(-c3ccc(cc3Cl)C(=O)c3ccccc3)c12)C1CCC1 Show InChI InChI=1S/C23H19ClN4O/c24-18-13-16(21(29)14-5-2-1-3-6-14)9-10-17(18)19-20-22(25)26-11-12-28(20)23(27-19)15-7-4-8-15/h1-3,5-6,9-13,15H,4,7-8H2,(H2,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC US Patent					Assay Description AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.				US Patent US8481733 (2013) BindingDB Entry DOI: 10.7270/Q2XD109J
					More data for this Ligand-Target Pair