null
SMILES: Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)-c1cccc(O)c1
InChI Key: InChIKey=CMCNTAYCGXAFFL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Activated CDC42 kinase 1 (Homo sapiens (Human)) | BDBM98332![]() (US8481733, 144) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 348 | n/a | n/a | n/a | n/a | n/a | n/a |
OSI Pharmaceuticals, LLC US Patent | Assay Description AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity. | US Patent US8481733 (2013) BindingDB Entry DOI: 10.7270/Q2XD109J | |||||||||||
More data for this Ligand-Target Pair |