BDBM98336 US8481733, 148

SMILES: Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)-c1ccoc1

InChI Key: InChIKey=TUGZHCPNPTWOOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM98336 (US8481733, 148) Show SMILES Nc1nccn2c(nc(-c3ccc(Oc4ccccc4)cc3)c12)-c1ccoc1 Show InChI InChI=1S/C22H16N4O2/c23-21-20-19(25-22(16-10-13-27-14-16)26(20)12-11-24-21)15-6-8-18(9-7-15)28-17-4-2-1-3-5-17/h1-14H,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC US Patent					Assay Description AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.				US Patent US8481733 (2013) BindingDB Entry DOI: 10.7270/Q2XD109J
					More data for this Ligand-Target Pair