BDBM98846 US8487093, 264
SMILES: OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)OCC2CNCCCO2)C1=O
InChI Key: InChIKey=JOCNFPCECUDFRC-FBKFWFMHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase (AmpC) (Pseudomonas aeruginosa) | BDBM98846 (US8487093, 264) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay. | US Patent US8487093 (2013) BindingDB Entry DOI: 10.7270/Q2057DKK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase (KPC-2) (Klebsiella pneumoniae) | BDBM98846 (US8487093, 264) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay. | US Patent US8487093 (2013) BindingDB Entry DOI: 10.7270/Q2057DKK | |||||||||||
More data for this Ligand-Target Pair |