BDBM98900 US8497265, 226

SMILES: OCC1CCN(CC1)c1ccc(Br)c(OC2CN(C2)c2ccc3ccccc3n2)n1

InChI Key: InChIKey=VHGGASKYRFCBFP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase Type 10 (PDE10A) (Rattus norvegicus (rat))	BDBM98900 (US8497265, 226) Show SMILES OCC1CCN(CC1)c1ccc(Br)c(OC2CN(C2)c2ccc3ccccc3n2)n1 Show InChI InChI=1S/C23H25BrN4O2/c24-19-6-8-22(27-11-9-16(15-29)10-12-27)26-23(19)30-18-13-28(14-18)21-7-5-17-3-1-2-4-20(17)25-21/h1-8,16,18,29H,9-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.229	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair